CoinDesk Indices presents its daily market update, highlighting the performance of leaders and laggards in the CoinDesk 20 Index.

The CoinDesk 20 is currently trading at 3239.11, down 3.2% (-107.44) since 4 p.m. ET on Thursday.

None of the 20 assets are trading higher.

Leaders: SOL (-1.1%) and BCH (-1.8%).
Laggards: SUI (-6.8%) and NEAR (-5.8%).

The CoinDesk 20 is a broad-based index traded on multiple platforms in several regions globally.

Medical equipment company Semler Scientific (SMLR) announced its third-largest bitcoin BTC purchase since adopting a bitcoin standard roughly one year ago.

The company in the ten days ending May 22 acquired 455 BTC for $50 million, averaging $109,801 per bitcoin. This acquisition, funded through its at-the-market (ATM) equity offering program, brings Semler’s total holdings to 4,264 BTC, purchased for $390 million and currently valued at more than $450 million.

To date, the company has issued 3,003,488 shares under its April 15 $500 million ATM program, raising $114.8 million.

Now roundly used as a key performance indicator by most companies adding bitcoin to their balance sheet, Semler’s BTC Yield, has risen to 25.8% in 2025. BTC Yield measures the year-to-date percentage change in the ratio of total bitcoin holdings to assumed diluted shares outstanding.

SMLR shares are lower by 5.3% in premarket trading alongside a sizable decline in the price of bitcoin Friday morning to $108,300.

Cryptocurrency lender Ledn is removing support for ether ETH and will begin offering a bitcoin-only loan model starting July 1 as it looks to simplify its product and sharpen its focus around bitcoin BTC.

The Cayman Islands-registered company may be attempting to broaden its appeal among the corners of the crypto community that say BTC is the only cryptocurrency that is needed. Such BTC advocates are often referred to as «Bitcoin Maxis.»

“With our new hyper-focus on Bitcoin-only lending, we’re going back to our roots and principles that inspired Bitcoin to begin with,” co-founder Adam Reeds said in an emailed announcement on Friday.

Ledn will also stop lending client assets to generate yield as it seeks to remove risk from its business model. Bitcoin offered to Ledn as collateral for loans will remain fully in its custody or that of its partners, Ledn said.

«Traditional finance relies on constantly reusing client assets to create leverage and, ultimately, inflation,» Reeds said. «Bitcoiners instinctively reject that model.»

Cryptocurrency lending was a major casualty of crypto winter in 2022, with the companies including BlockFi, Voyager, Celsius and Genesis going to the wall.

Ledn managed to survive and is now attempting to resurrect the BTC-backed lending sector, with its simplified product offering and helped by the friendlier regulatory approach to crypto in the U.S, co-founder Mauricio Di Bartolomeo told CoinDesk in a recent interview.